The 2012 McWhorter School of Pharmacy Summer Internship Research Award Recipients
Ms. Alyssa Nweeia, class of 2015 is working with Dr. Danielle Cruthirds to determine the effect on oxidant production of various classes of medications used in the treatment of Attention Deficit Hyperactivity Disorder. Specifically, she is evaluating whether there is a correlation between levels of oxidant production and likelihood of cardiac events associated with the use of these medications.
Ms. Bethany Bentley, class of 2015 is working with Dr. Danielle Cruthirds to determine the effect on oxidant production of various classes of medications used in the treatment of depression. Specifically, she is evaluating whether there is a correlation between levels of oxidant production and severity of adverse effects associated with the use of these medications.
Ms Jordan Burt class of 2014 is currently busy with her project exploring the biopharmaceutics of ophthalmic polymeric drug delivery systems. Her goal is to develop a sustained release drug formulation, via the microencapsulation of tetracycline, intended for the treatment of trachoma which is the world's leading cause of preventable blindness. Ms Burt’s mentor is Dr. John Arnold.
Mr. Chase Carpenter class of 2015 is working with Dr. David Luthin to optimize sample processing methodologies utilizing solid-phase extraction (SPE) for improved accuracy and precision of measuring estrogenic compounds in rivers and streams using LC-MS/MS.
Ms. Gwen Nance class of 2015 is working with Dr. Teresa Wilborn to study differences in metabolism of raloxifene and tamoxifen in endometrial cancer and breast cancer cell lines in order to gain insight into differences in therapeutic and toxic activities of these drugs. She is also studying the sulfate conjugation activity of three enzymes toward raloxifene and tamoxifen metabolites in- vitro in order to determine which of these enzymes is most likely to be producing these conjugates in-vivo.
Ms. Bethany Rasberry class of 2014 and Ms Adrienne Darby class of 2015 are working with Dr. Greg Gorman in evaluating the impact of commonly used alternative medicines and supplements on the efficacy of various orally administered chemotherapeutic prodrugs by studying differences in drug activation utilizing in vitro metabolism as a function of potential inhibitor concentration.